Lite-Motifs
Overall Goals
Relevance to our proteomics work
Relevance to our proteomics work (cont.)
Possible Approaches
PSSMs
Describing motifs using frequency matrices
Example frequency matrix
PSSMs/Profiles
Learning PSSMs
Problems with PSSMs
Cobbling
Cobbler Illustration
Family Pairwise Search
Which method is best?
Comparison Protocol
Results
Conclusion
Which is best (part 2)?
Email: murphy@cmu.edu
Home Page: http://www.andrew.cmu.edu/user/murphy