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Murphy Lab - Software - 2019 - PC12 Differentiation


The software and data used for the following paper can be downloaded below:

Xiongtao Ruan, Gregory R. Johnson, Iris Bierschenk, Roland Nitschke, Melanie Boerries, Hauke Busch and Robert F. Murphy (2019) Image-derived models of cell organization changes during differentiation and drug treatments. Molecular Biology of the Cell 31:655-666. [DOI]

Source Code

Input Images

  • PC12_images.tgz (21Gb) These are the original images in Zeiss format. They are described here. They are also available in OME-TIFF format from Data Dryad below.
  • Data Dryad (18Gb)
  • Intermediate Results

    • PC12_intermediate_results.tgz (23GB) This file contains all of the results generated from the raw images by the source code. It can be used to reproduce all of the figures and tables.



  • Last Updated: 14 Jul 2020




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