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Murphy Lab
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Murphy Lab - Research Projects
Descriptions of Past Projects
The most recent descriptions of our work can be found in papers on the
publications page. The descriptions of the projects below are maintained for
historical reference.
Interpretation of Protein Location Patterns from Fluorescence
Microscope Images
Objective Comparison of Biomedical Imaging Experiments
(Edward J. S. Roques,
Graduate Student in Biological Sciences)
Extracting and Classifying Fluorescence Microscope Images of Cells from Online Journals
(Jie Yao,
Graduate Student at the Center for Automated Learning and Discovery, and
Meel Velliste, Graduate Student in Biomedical Engineering)
Automated Classification of Protein Location Patterns from Fluorescence Microscopy:
Phase 3 - Classification of 3-Dimensional Protein Location Patterns
(Meel Velliste,
Graduate Student in Biomedical Engineering, and Aaron Rising,
Undergraduate Student in Biological Sciences)
Automated Classification of Protein Location Patterns from Fluorescence Microscopy:
Phase 4 - Object-level Recognition of Protein Subcellular Location Patterns
(Meel Velliste,
Graduate Student in Biomedical Engineering, and Michael V. Boland,
former Graduate Student in Biomedical Engineering)
Source and Resolution Independent Classification of Protein Location
Patterns in Fluorescence Microscope Images
(Gregory Porreca, former Student in the Summer Undergraduate Research
Program, and Meel Velliste, Graduate Student in Biomedical Engineering)
Methods for the objective selection of representative fluorescence
microscope images: TypIC2
(Jennifer Lin,
Undergraduate Student in Biological Sciences, James A. Gajnak, former
Undergraduate in Biological Sciences and Computer Science, and Michael V.
Boland, former Graduate Student in Biomedical Engineering)
Building Multimedia Knowledge Bases of Protein Subcellular Location
Information
(Kai Huang, Graduate Student in Biological Sciences, and Jennifer
Lin, Undergraduate Student in Biological Sciences)
Endosomal pH Regulation in Erythroid and Non-Erythroid Cells
References
to Literature describing Differences in Endosomal pH between Cell
Types
Endosomal pH Regulation
(Jeong-Ah Kwon,
Graduate Student in Biological Sciences)
Interpretation of Protein Location Patterns from Fluorescence
Microscopy
Automated Classification of Protein Location Patterns from Fluorescence Microscopy:
Phase 1
- Resolution of Five Classes of Patterns in Chinese Hamster Ovary Cells
(Michael
V. Boland, former Graduate Student in Biomedical Engineering,and
Mia K. Markey, former Undergraduate in Biological
Sciences)
Automated Classification of Protein Location Patterns from
Fluorescence Microscopy: Phase 2 - Extension to Ten Classes of
Patterns in HeLa Cells and Resolution of Similar Patterns
(Michael
V. Boland, former Graduate Student in Biomedical Engineering)
Methods for the
objective selection of representative fluorescence microscope images
(Mia K. Markey,
former Undergraduate in Biological Sciences, and Michael V. Boland,
former Graduate Student in Biomedical Engineering)
Endosomal pH Regulation in Erythroid and Non-Erythroid Cells
References
to Literature describing Differences in Endosomal pH between Cell
Types Theoretical
Modeling of Endosomal pH Regulation
(Sheree L. Rybak,
former Graduate Student in Biological Sciences, in collaboration with
Dr.
Fred Lanni, Associate Professor of Biological
Sciences)
Genes required for Receptor Recycling after Endocytosis
Identification of Genes Capable of Rescuing the
Temperature-Conditional Defects in the End6 mutant of Chinese Hamster
Ovary Cells
(E. John Meharra, former Graduate Student in
Biological Sciences, Jeong-Ah Kwon, Graduate Student in
Biological Sciences, and Yue Mary Yang, former Undergraduate in
Biological Sciences)
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